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9 Best Peptide Anti-wrinkle Serums/Creams for Sagging Skin

9 Best Peptide Anti-wrinkle Serums/Creams for Sagging Skin

    • You may have heard of peptides as an anti-aging essential and heroic ingredient that smoothes, repairs and moisturizes the skin, but have you ever wondered what a peptide is and what it does for the skin, exactly? More important, use it as one of the key ingredients in your skin care product, which is worth the price? Here, with best peptide-infused skin care formulas to look out for, we will share top peptide anti-wrinkle serums/creams for sagging skin.
  • What Are Peptides and What Do They Do?

Human skin is comprised mostly of collagen. Collagen is a protein comprised of long segments of amino acids arranged like a chain.

When collagen breaks down, short segments of amino acids are formed. These are the tiny proteins and active molecules known as peptides.

Peptides serve as the building blocks for not only new collagen but also elastin fibers. These fibers are the building blocks of our skin and add to tissue firmness and elasticity.

Aside from being essential to the skin’s structure and function (important factors in firmness, texture and overall appearance), peptides are found in every human cell and play an important role in how the body functions, often acting as a biologic messenger.

  • How Peptides in Your Skin Care Work?

When collagen is depleted by age and environmental factors, including sunlight, it is not fully replaced. As a result, smooth, young skin slowly becomes thinner and wrinkled over time. So you can successfully minimize wrinkles and give your skin a more youthful appearance with the application of skin care peptides that trigger the production of collagen. It is therefore important to use a good peptide wrinkle cream.

The most commonly used peptide in skin care is Matrixyl (palmitoyl- or oligopeptide pentapeptide). This is a neuropeptide that reduces fine lines very well. 

Wrinkle creams containing anti aging peptides are popular and effective skin care products. Argireline (Acetyl hexapeptide) has been marketed as a safer, less expensive, and non-invasive alternative to Botox. This anti-aging peptide works by causing facial muscles to relax, thereby minimizing wrinkles. It is often combined with Leuphasyl, which relaxes tiny muscles under the skin. This is particularly helpful for fading wrinkles around the eyes and for forehead wrinkles.

Octapeptide is a lengthened version of Argireline. By making the small muscles under your skin longer and reducing muscle tension, octapeptide fades the appearance of fine lines.

Palmitoyl pentapeptide, more commonly known as Matrixyl 3000 is included in many anti-aging product preparations and includes of two paired amino acids attached to a fatty acid to promote absorption.

  • Best Peptide Anti-wrinkle Serums/Creams for Sagging Skin

| Olay Regenerist Regenerating Serum Fragrance-Free

Olay Regenerist Regenerating Serum Fragrance-Free

Containing Olay's Amino-Peptide Complex II, this formula is designed to deliver moisturizing ingredients 10 layers deep into the skin's surface. Plus, its exfoliating properties aid in surface cell turnover and help regenerate surface skin cells. Its expert formula is non-greasy and absorbs quickly into the skin's surface.

| Olay Regenerist Micro-Sculpting Cream Fragrance-Free

Olay Regenerist Micro-Sculpting Cream Fragrance-Free

Infused with Hyaluronic Acid, Amino-Peptides and Niacinamide (Vitamin B3), this moisture-binding formula instantly plumps and lifts surface cells. The luxurious-feeling moisturizer immediately leaves skin hydrated, softens the look of fine lines and wrinkles and firms the look of skin with plumping hydration.

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| Drunk Elephant Protini Polypeptide Cream

Drunk Elephant Protini Polypeptide Cream

This breakthrough protein moisturizer combines an unprecedented array and concentration of signal peptides, growth factors, supportive amino acids and pygmy waterlily for visible and immediate improvement in the appearance of skin’s tone, texture and firmness.

| Paula's Choice Peptide Booster

Paula's Choice Peptide Booster

Peptide Booster is a powerful blend that targets eight different anti-aging concerns, from fine lines and wrinkles to uneven complexions. Tripeptide-1 works to enhance firmness, Azelaoyl Bis-Dipeptide-10 helps with discoloration and Hexanoyl Dipeptide-3 Norleucine Acetate encourages the skin to shed properly so it's rejuvenated and younger-looking.

It also contains hydrating amino acids and repairing ingredients to help skin feel firmer and more resilient, and reduce the appearance of lines.

| Peter Thomas Roth Peptide 21 Wrinkle Resist Serum

Peter Thomas Roth Peptide 21 Wrinkle Resist Serum

Packed with a 73% complex of 21 Peptides and Neuropeptide Complex, this revolutionary wrinkle-fighting serum helps to visibly reduce the look of fine lines and wrinkles.
It contains gamma proteins harness the power of Asian natto gum, a breakthrough ingredient that helps improve the look of elasticity, radiance, uneven skin tone, and texture. This formula is also infused with squalane, a hyaluronic acid complex, and vitamins A, C, and E.

| SkinMedica TNS Essential Serum

SkinMedica TNS Essential Serum

This TNS serum contains two separate formulations, APS Corrective Complex and TNS Recovery Complex, that work in synergy to smooth the appearance of fine lines and improve overall tone and texture.  APS Corrective Complex is a blend of antioxidants and peptides that improves the skin's overall appearance. TNS Recovery Complex is a mix of growth factors, matrix proteins and antioxidants that softens fine lines and wrinkles. Patented TNS helps improve the appearance of fine lines, wrinkles, large pores, skin tone and texture.

| Neocutis Bio-Cream Bio-Restorative Skin Cream

Neocutis Bio-Cream Bio-Restorative Skin Cream

The first and original skin cream formulated with PSP which stands for “processed skin cell proteins,” is a blend of proteins and polypeptides, available to rejuvenate, soothe skin and increase firmness, brightness and elasticity. It’s a dermatologist favorite for sensitive skin.

| PCA Skin ExLinea Peptide Smoothing Serum

PCA Skin ExLinea Peptide Smoothing Serum

This serum minimizes the appearance of fine lines and wrinkles with a blend of peptides and hydrating emollients. The anti-aging formula features hyaluronic acid to continually moisturize your skin while rice bran wax leaves a smooth appearance. Vitamin E neutralizes free radicals to help prevent premature aging.

| iS Clinical Super Serum Advance Plus

iS Clinical Super Serum Advance Plus

Formulated with Copper tripeptide growth factor plus a 15 percent concentration of Vitamin C, this super serum helps smooth skin and improve scar tissue, stretch marks and uneven skin. Known for its wound-healing powers, copper tripeptide is released naturally in the body during an injury, making it a perfect regenerating compound to be utilized in the skin.

It also contains powerful botanical antioxidants and safe skin lighteners.

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