Ingredients Review: NEW Paula's Choice 25% Vitamin C + Glutathione Clinical Serum

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Paula's Choice 25% Vitamin C + Glutathione Clinical Serum

WHERE TO BUY: 

$62/30ml; Paula's Choice (up to 7% cashback from Extrabux)

$62/30ml; Sephora (up to 4% cashback from Extrabux)

Julio Lamberty, director of innovation and formula development at Paula's Choice, explains that vitamin C—which is one of the main antioxidants in your skin—improves sensitive skin's ability to withstand visible changes from external stressors (think: UV rays, blue light, and pollutants.) But the benefits of a strong vitamin C extend beyond surface-level protection. "Vitamin C and its derivatives also help bolster skin's immune system by protecting Langerhans cells from UV radiation. These specialized immune cells help protect skin's living layers from more serious, irreversible damage," says Lamberty. While your skin naturally contains some vitamin C from dietary and supplemental sources, environmental exposure can erode these reserves over time.

25% Vitamin C + Glutathione Clinical Serum is formulated with a highly stable blend of oil-and-water soluble vitamin C for optimal effectiveness. Glutathione + GAP technology (glutathione amino acid precursors) work to minimize irritation while amping up antioxidant protection and ingredient stability. This clinical-level formula helps sustain a natural level of glutathione & vitamin C within skin's most uppermost layers for extended results, while reducing oxidative stress that triggers discoloration.

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Key Ingredients & Benefits

Key Ingredients:

- 25% Vitamin C

First, the brightening promise comes via a clever blend of two forms of Vitamin C. Paula's Choice uses a 25% concentration of oil-soluble Tetrahexyldecyl Ascorbate and water-soluble Ascorbyl Glucoside. Unlike the ubiquitous L-Ascorbic Acid, these are extremely stable and won’t oxidize. You don’t have to worry about triggering sensitivities that turn your skin red and inflamed either. The combination of Glycerin with a touch of Dimethicone gives this serum a silky texture that feels almost luxe when applied. 

- Glutathione

Glutathione is another hero ingredient in this impressive formula. A potent antioxidant, it successfully defends against free radical damage like UV exposure and pollution. 

Glutathione is a tripeptide comprised of three amino acids (cysteine, glutamic acid, and glycine), which work in unison when used topically to brighten a dull complexion while offering skin-restoring benefits. 

Glutathione has also been shown to help stabilize and enhance the performance of other antioxidants such as vitamin C, even when used in low concentrations.

- Ergothioneine

Maximizing antioxidant protection, the serum highlights Vitamin E, Apple Fruit Extract, and mushroom derived Ergothioneine.

Several studies have shown that ergothioneine is a potent antioxidant, capable of helping skin look younger when exposed to environmental stressors and sources of oxidative damage. One of the ways ergothioneine works on skin is by helping to protect its endogenous (naturally occurring) antioxidants from degrading, thus enabling it to maintain its defenses for longer periods of time.

Ergothioneine also has a surface inhibitory effect on an enzyme that plays a role in fueling excess melanin within skin's uppermost layers. In doing so, ergothioneine plays a supporting role helping to fade discolorations.

Benefits:

• Targets sun damage & improves uneven tone

• Boosts radiance & helps prevent discoloration

• Visibly firms & improves elasticity

• GAP technology reduces oxidative stress & targets discoloration

• Lightly hydrating serum for all skin types

Clinical Results:

• 94% had visibly improved discolorations

• 91% had brighter-looking skin

Review

When it comes to high concentrations of Vitamin C, it's important to consider factors like your skin concerns, your skin's sensitivity and any potential for irritation. When used in a well-formulated serum, 25% concentrations is effective at delivering the best Vitamin C has to offer your skin – and your longterm skin health.

While the high concentration of Tetrahexyldecyl Ascorbate in the Paula's Choice 25% Vitamin C + Glutathione Serum is exceptional, it's not the only feature that makes the new formula innovative. The true innovation derives from the inclusion of both Glutathione and “Glutathione amino acid precursors” – which the brand refers to as GAP technology. 

These combine to "minimize irritation while amping up antioxidant protection and ingredient stability." That's how you get to a 25% Vitamin C concentration without risk of irritation. 

The small, orange bottle isn't overly ostentatious in any way and the serum itself is opaque white in color. It's fragrance-free, and the consistency is creamy and silky. It feels super hydrating on the skin, but not too heavy either. 

If you're looking for a serum that offers a one-stop solution to various skin-care concerns while focusing on gentle, transparent ingredients, this serum is undoubtedly worth adding in to your routine.

The Comparison with C15 Super Booster

Paula's Choice offers two concentrations of vitamin C, our C15 Booster with 15% stabilised ascorbic acid for all over use and C25 Super Booster with 25% stabilised ascorbic acid. Lower concentrations of vitamin C are also good for your skin, providing cumulative benefits in leave-on products such as a vitamin C moisturiser or an anti-ageing vitamin C serum. 

How is the new 25% Vitamin C + Glutathione Clinical Serum different from the C15 Super Booster? Here's the breakdown!

Benefits: Serum will benefit stubborn sun damage & discoloration while the Booster helps boost radiance & brighten dullness.

Texture: Serum is a silky lotion, while the Booster is a lightweight liquid. Both were formulated for all skin types to use.

Vitamin C: Serum contains 25% vitamin C derivatives (23% tetrahexyldecyl ascorbate⁠ & 2% ascorbyl glucoside⁠); the Booster uses 15% ascorbic acid (AKA pure vitamin C).

Supporting Ingredients: Serum is supported by antioxidant glutathione & a new GAP technology; Booster costars ferulic acid, vitamin E & hyaluronic acid.

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